When the body is infected with the coronavirus, the specific protein of the virus stimulates the immune system and lead to an antibody response, the first antibody to appear is IgM, and then the IgG antibody. From the general process of acute infection, when the IgG antibody appears, the concentration will continue to increase, the IgM will continue to decrease or even disappear, and the IgG antibody will exist for a long time. The simultaneous dynamic monitoring of IgM and IgG antibody on be used in the auxiliary diagnosis of new corona virus infection.